The regarded impression of those PTMs on ATXN2’s purpose and SCA2 pathogenesis remains confined. In other polyQ diseases, numerous research suggested that proteolytic cleavage of polyQ proteins could play a very important position in pathogenesis [36, 45]. Aligned with this particular plan, the presence of the enriched 42 kDa fragment from https://c64644321.blog4youth.com/28849704/isa-2011b-for-dummies