Below, we demonstrate that conolidine, a natural analgesic alkaloid used in classic Chinese medication, targets ACKR3, therefore delivering further proof of the correlation among ACKR3 and discomfort modulation and opening alternate therapeutic avenues with the treatment method of Persistent agony. We demonstrated that, in contrast to classical opioid receptors, https://www.proleviate.com/post/what-are-the-side-effects-of-conolidine