John's Wort (Hypericum perforatum) may improve the metabolism of tricyclic antidepressants and bring about reduced plasma levels of tricyclic antidepressants and minimized antidepressant reaction. During the existence of ethanol amitriptyline free plasma concentrations and nortriptyline concentrations had been improved. Amitriptyline plasma concentration could be amplified by sodium v... https://jeang703ces2.celticwiki.com/user